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Evidence-graded profiles for 40+ peptides. Side-by-side comparisons, FDA status tracking, dosing protocols, and safety data — all independent, all free.
Trending Peptides in 2026
The most searched and studied peptides right now, ranked by evidence quality.
BPC-157
B+A 15-amino-acid peptide derived from gastric juice. The most popular recovery peptide with 100+ preclinical studies showing accelerated healing of tendons, ligaments, muscle, gut lining, and nerves.
TB-500
BA synthetic fragment of thymosin beta-4 that promotes cell migration, blood vessel formation, and tissue repair. Often stacked with BPC-157 as the 'Wolverine Stack.'
Semaglutide
A+A GLP-1 receptor agonist and the gold standard for evidence-based weight loss peptide therapy. Demonstrated 14.9–16.9% mean body weight reduction in the landmark STEP trials.
Tirzepatide
A+A dual GIP/GLP-1 receptor agonist that achieved up to 22.5% mean weight loss in the SURMOUNT-1 trial — the highest of any FDA-approved weight loss medication.
Find Peptides by Goal
Not sure where to start? Browse peptides by what you're trying to achieve.
Head-to-Head Comparisons
Side-by-side breakdowns of the most commonly compared peptides.
FDA-Approved Peptides
These peptides have the highest level of clinical evidence and are approved by the FDA for specific indications.
Semaglutide
FDA ✓FDA-approved for weight management and type 2 diabetes
A GLP-1 receptor agonist and the gold standard for evidence-based weight loss peptide therapy. Demonstrated 14.9–16.9% mean body weight reduction in the landmark STEP trials.
Tirzepatide
FDA ✓FDA-approved for weight management and type 2 diabetes
A dual GIP/GLP-1 receptor agonist that achieved up to 22.5% mean weight loss in the SURMOUNT-1 trial — the highest of any FDA-approved weight loss medication.
PT-141
FDA ✓FDA-approved for hypoactive sexual desire disorder (HSDD) in women
A melanocortin receptor agonist that works directly on the nervous system to increase sexual desire. The only FDA-approved peptide for sexual dysfunction that acts on the brain rather than vascular system.
Tesamorelin
FDA ✓FDA-approved for HIV-associated lipodystrophy
An FDA-approved GHRH analog that stimulates natural growth hormone production. Clinically proven to reduce visceral adipose tissue and increasingly used off-label for body recomposition.
Sermorelin
FDA ✓FDA-approved (1990) for pediatric growth hormone deficiency; off-label adult use via compounding pharmacies
The original synthetic GHRH(1–29) and the most accessible GH-stimulating peptide for age-related hormone decline. Stimulates the body's own pulsatile GH release rather than replacing it.
Liraglutide
FDA ✓FDA-approved for weight management (Saxenda) and type 2 diabetes (Victoza)
The original once-daily GLP-1 receptor agonist. Lower weight-loss magnitude than semaglutide but a longer real-world track record across diabetes and obesity.
Afamelanotide
FDA ✓FDA-approved (2019) for erythropoietic protoporphyria (EPP)
An FDA-approved selective MC1R agonist used to increase eumelanin density in erythropoietic protoporphyria patients. Off-label cosmetic tanning use is widespread internationally.
Gonadorelin
FDA ✓FDA-approved (Factrel) historically for diagnostic GnRH stimulation; off-label use in TRT to preserve testicular function
Synthetic GnRH used clinically to stimulate LH/FSH release. In testosterone replacement therapy, used pulsatile to preserve testicular size and fertility instead of hCG.
GHRH (1–44)
FDA ✓FDA-approved (Geref) historically as diagnostic GH stimulant; current US availability limited
The full 44-amino-acid GHRH sequence. The natural pituitary stimulus for GH release. Largely supplanted in clinical use by sermorelin/tesamorelin but remains a research and diagnostic tool.
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